OX40 Ligand/TNFSF4, Human (HEK293, His)

MedChem Express

OX40 Ligand/TNFSF4, Human (HEK293, His)

10

Research Use Only

98.0

TNFSF4

TNF superfamily member 4

CD134L, CD252, GP34, OX-40L, OX4OL, TNLG2B, TXGP1, tumor necrosis factor ligand superfamily member 4, CD134 ligand, OX40 antigen ligand, glycoprotein Gp34, tax-transcriptionally activated glycoprotein 1 (34kD), tumor necrosis factor (ligand) superfamily member 4, tumor necrosis factor ligand 2B, tumor necrosis factor superfamily member 4

Tumor necrosis factor ligand superfamily member 4

OX40 Ligand (TNFSF4) is a type II glycoprotein with a cytoplasmic tail of 23 aa and an extracellular domain of 133 aa[1]. OX40 Ligand is a ligand for TNFRSF4 (CD134), belongs to tumor necrosis factor (TNF) family. OX40 Ligand can activate OX40 and thereby functioning as a T cell co-stimulatory molecule. The OX40-OX40 Ligand interaction promotes effector T-cell survival and effectively induces memory T-cell generation, as well as enhances the helper function of Tfh for B cells, and also promotes the differentiation and maturation of DCs[1][2]. OX40 Ligand/TNFSF4 Protein, Human (HEK293, His) is a recombinant human OX40 Ligand (Q51-L183) with N-terminal 6*His tag, which is produced in HEK293.

-20°C

41116100

Human