OX40 Ligand/TNFSF4, Rat (HEK293, Fc)

MedChem Express

OX40 Ligand/TNFSF4, Rat (HEK293, Fc)

10

Research Use Only

98.0

Tnfrsf4

TNF receptor superfamily member 4

Ox40, Txgp1, tumor necrosis factor receptor superfamily member 4, MRC OX40, OX40 antigen, OX40L receptor, Tax-transcriptionally activated glycoprotein 1, tumor necrosis factor (ligand) superfamily member 4, tumor necrosis factor receptor superfamily, member 4, tumor necrosis factor superfamily, member 4

Tumor necrosis factor receptor superfamily member 4

OX40 Ligand (TNFSF4) is a type II glycoprotein with a cytoplasmic tail of 23 aa and an extracellular domain of 133 aa[1]. OX40 Ligand is a ligand for TNFRSF4 (CD134), belongs to tumor necrosis factor (TNF) family. OX40 Ligand can activate OX40 and thereby functioning as a T cell co-stimulatory molecule. The OX40-OX40 Ligand interaction promotes effector T-cell survival and effectively induces memory T-cell generation, as well as enhances the helper function of Tfh for B cells, and also promotes the differentiation and maturation of DCs[1][2]. OX40 Ligand/TNFSF4 Protein, Rat (HEK293, Fc) is a recombinant rat OX40 Ligand (V20-P210) with C-terminal hFc tag, which is produced in HEK293.

-20°C

41116100