Oxaprozin-d5 [2933758-40-6]

MedChem Express

Oxaprozin-d5 [2933758-40-6]

5

CHEMICAL,detergents_surfactants

Research Use Only

C18H10D5NO3

298.35

Oxaprozin-d5 is deuterium labeled Oxaprozin. Oxaprozin is an inhibitor of both COX-1 and COX-2 with IC50s of 2.2 microM and 36 microM for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-kappaB.

O=C(O)CCC1=NC(C2=CC=CC=C2)=C(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])O1

12352005