Oxaprozin (potassium) [174064-08-5]
HY-B0808A
CAS Number174064-08-5
Product group Chemicals
Molecular Weight331.41
Overview
- SupplierMedChem Express
- Product NameOxaprozin (potassium) [174064-08-5]
- Delivery Days Customer10
- CAS Number174064-08-5
- CertificationResearch Use Only
- Molecular FormulaC18H14KNO3
- Molecular Weight331.41
- Scientific DescriptionOxaprozin potassium is an orally active and potent COX inhibitor, with IC50 values of 2.2 microM for human platelet COX-1 and and 36 microM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium also inhibits the activation of NF-kappaB. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium shows anti-inflammatory activity. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-kappaB pathway contributes to its anti-inflammatory properties[1][2].
- SMILESO=C(O[K])CCC1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)O1
- UNSPSC12352200