Oxyberberine [549-21-3]
HY-N5027
CAS Number549-21-3
Product group Chemicals
Estimated Purity99.85
Molecular Weight351.35
Overview
- SupplierMedChem Express
- Product NameOxyberberine [549-21-3]
- Delivery Days Customer10
- CAS Number549-21-3
- CertificationResearch Use Only
- Estimated Purity99.85
- Molecular FormulaC20H17NO5
- Molecular Weight351.35
- Scientific DescriptionOxyberberine (Oxyberberin; Berlambine) is an orally effective heme oxygenase HO-1 agonist that can activate antioxidant mechanisms by regulating the PI3K/Akt/AMPK signaling pathway. Oxyberberine induces HO-1 expression, increases SOD and GSH-Px activity, inhibits NF-kappaB-mediated inflammatory responses, and improves insulin sensitivity and glucose metabolism. Oxyberberine has anti-diabetic, neuroprotective, anti-inflammatory and antioxidant effects, and can be used to study type 2 diabetes, traumatic brain injury (TBI) and inflammatory bowel disease[1][2][3].
- SMILESO=C(C1=C(OC)C(OC)=CC=C1C=C23)N2CCC(C3=C4)=CC5=C4OCO5
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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