P-1075

MedChem Express

P-1075 [60559-98-0]

10

60559-98-0

99.81

C12H17N5

231.30

P-1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-K IR 6) , with an EC 50 value of 45 nM for SUR2B-K IR 6 channel activation [1] . P-1075 also P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts [2] .

CCC(N/C(NC#N)=N/C1=CC=CN=C1)(C)C

-20°C,2°C to 8°C

12352200