P-gp/BCRP-IN-2

TargetMol Chemicals

P-gp/BCRP-IN-2

16

Chemical

Research Use Only

P-gp/BCRP-IN-2

C32H35N3O6

557.64

P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP (IC50: 600 nM). Additionally, it bolsters the anti-proliferative impact of Doxorubicin in the drug-resistant HT29/DX and MDCK-MDR1 human adenocarcinoma colon cancer cell lines [1].

3 years

-20°C

51202000