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p-nitro-Pifithrin-alpha [389850-21-9]

HY-130437
MedChem Express
CAS Number389850-21-9
Product group Chemicals
Estimated Purity97.0
Molecular Weight398.27
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Overview

  • Supplier
    MedChem Express
  • Product Name
    p-nitro-Pifithrin-alpha [389850-21-9]
  • Delivery Days Customer
    5
  • CAS Number
    389850-21-9
  • Certification
    Research Use Only
  • Estimated Purity
    97.0
  • Hazard Information
    h302-h315-h319-h335,p261-p264-p270-p271-p280-p302+p352-p304+p340-p305+p351+p338-p330-p362+p364-p403+p233-p405-p501
  • Molecular Formula
    C15H16BrN3O3S
  • Molecular Weight
    398.27
  • Scientific Description
    p-nitro-Pifithrin-alpha, a cell-permeable analog of pifithrin-alpha, is a potent p53 inhibitor. p-nitro-Pifithrin-alpha suppresses p53-mediated TGF-beta1 expression in HK-2 cells. p-nitro-Pifithrin-alpha inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. p-nitro-Pifithrin-alpha attenuates steatosis and liver injury in mice fed a high-fat diet [4]. non-alcoholic fatty liver disease[1][2][3].
  • SMILES
    N=C1SC2=C(CCCC2)N1CC(C3=CC=C([N+]([O-])=O)C=C3)=O.[H]Br
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200