p-nitro-Pifithrin-alpha [389850-21-9]
HY-130437
CAS Number389850-21-9
Product group Chemicals
Estimated Purity97.0
Molecular Weight398.27
Overview
- SupplierMedChem Express
- Product Namep-nitro-Pifithrin-alpha [389850-21-9]
- Delivery Days Customer5
- CAS Number389850-21-9
- CertificationResearch Use Only
- Estimated Purity97.0
- Hazard Informationh302-h315-h319-h335,p261-p264-p270-p271-p280-p302+p352-p304+p340-p305+p351+p338-p330-p362+p364-p403+p233-p405-p501
- Molecular FormulaC15H16BrN3O3S
- Molecular Weight398.27
- Scientific Descriptionp-nitro-Pifithrin-alpha, a cell-permeable analog of pifithrin-alpha, is a potent p53 inhibitor. p-nitro-Pifithrin-alpha suppresses p53-mediated TGF-beta1 expression in HK-2 cells. p-nitro-Pifithrin-alpha inhibits the activation of caspase-3 by Zika virus (ZIKV) strains. p-nitro-Pifithrin-alpha attenuates steatosis and liver injury in mice fed a high-fat diet [4]. non-alcoholic fatty liver disease[1][2][3].
- SMILESN=C1SC2=C(CCCC2)N1CC(C3=CC=C([N+]([O-])=O)C=C3)=O.[H]Br
- Storage Instruction-20°C
- UNSPSC12352200
![p-nitro-Pifithrin-alpha [389850-21-9]](https://www.targetmol.com/group3/M00/35/5C/CgoaEWayHVuEHkghAAAAABKjRxI336.png)