P300 bromodomain-IN-1

MedChem Express

P300 bromodomain-IN-1

10

Research Use Only

C29H31ClN4O4

535.03

P300 bromodomain-IN-1 (Compoun 1u) is a potent p300 (EP300) bromodomain inhibitor with an IC50 of 49 nM. P300 bromodomain-IN-1 suppresses the expression of c-Myc and induces G1/G0 phase arrest and apoptosis in OPM-2 cells[1].

COC1=CC=C(C=C1Cl)N2C(C[C@H]2C3=NC4=CC(C5=C(ON=C5C)C)=CC=C4N3[C@H]6CC[C@@H](CC6)OC)=O

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