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p38 MAP Kinase Inhibitor IV [1638-41-1]

p38 MAP Kinase Inhibitor IV [1638-41-1]

T36011
TargetMol Chemicals
CAS Number1638-41-1
DownloadMSDS
Product group Chemicals
Molecular Weight456.94
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    p38 MAP Kinase Inhibitor IV [1638-41-1]
  • Delivery Days Customer
    44
  • CAS Number
    1638-41-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    p38 MAP Kinase Inhibitor IV
  • Molecular Formula
    C12H4Cl6O4S
  • Molecular Weight
    456.94
  • Scientific Description
    p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 microM for p38alpha, p38beta, p38x, and p38delta, respectively, in vitro.[1] It also inhibits LPS-induced TNF-alpha and IL-1beta cytokine production (IC50s = 22 and 44 nM, respectively) in human peripheral blood mononuclear cells.
  • Shelf life instruction
    3 years
  • SMILES
    Oc1c(Cl)cc(Cl)c(Cl)c1S(=O)(=O)c1c(O)c(Cl)cc(Cl)c1Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

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