p38 MAPK Antibody (Bi-Phospho-Thr180/Tyr182)

Aviva Systems Biology

p38 MAPK Antibody (Bi-Phospho-Thr180/Tyr182)

23

Working Dilutions: Dot Blot: 1:1000Western Blot: 1:1000IHC: 1:250

Dot Blot, Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

5730406E14Rik

RIKEN cDNA 5730406E14 gene

uncharacterized protein LOC70496

Rabbit

The three Mitogen-Activated Protein Kinases (MAPKs) are evolutionarily conserved protein kinases that control a vast array of cellular processes. p38 MAPK is one of these kinases and it is activated by both inflammatory cytokines and by stress (Johnson and Lapadat, 2002; Shi and Gaestel, 2002). The p38 MAPK is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system (Philip and Armstead, 2003; Ying et al., 2002). Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182 (Lin et al., 1995).

Human, Mouse, Rat

41116161