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Immunostaining of human breast cancer tissue showing p38 when phosphorylated at Thr180/Tyr182 in red using p38 MAPK (phospho Thr180/Tyr182) antibody (GTX48614)
Immunostaining of human breast cancer tissue showing p38 when phosphorylated at Thr180/Tyr182 in red using p38 MAPK (phospho Thr180/Tyr182) antibody (GTX48614)
Immunostaining of human breast cancer tissue showing p38 when phosphorylated at Thr180/Tyr182 in red using p38 MAPK (phospho Thr180/Tyr182) antibody (GTX48614)

p38 MAPK (phospho Thr180/Tyr182) antibody

GTX48614
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMapk14
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Overview

  • Supplier
    GeneTex
  • Product Name
    p38 MAPK (phospho Thr180/Tyr182) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    We recommend the following starting dilutions: For WB: Use at a dilution of 1:1000. For IHC: Use a dilution of 1:250. Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID81649
  • Target name
    Mapk14
  • Target description
    mitogen activated protein kinase 14
  • Target synonyms
    CRK1, CSBP, CSPB1, Csbp1, Csbp2, Exip, Hog, Mxi2, Prkm14, Prkm15, RK, Sapk2A, p38, p38Hog, p38alpha, mitogen-activated protein kinase 14, Csaids binding protein, MAP kinase 14, MAP kinase 2, MAP kinase Mxi2, MAP kinase p38 alpha, MAPK 14, MAX-interacting protein 2, cytokine suppressive anti-inflammatory drug binding protein, cytokine-supressive anti-inflammatory drug binding protein, mitogen-activated protein kinase 14A, mitogen-activated protein kinase p38 alpha, p38 MAP kinase, p38 mitogen activated protein kinase, p38alpha Exip, reactive kinase, stress-activated protein kinase 2A
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    mitogen-activated protein kinase; involved in intracellular signalling, inhibition of apoptosis and gene activation [RGD, Feb 2006]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Chiu YJ, Tsai FJ, Bau DT, et al. Next‑generation sequencing analysis reveals that MTH‑3, a novel curcuminoid derivative, suppresses the invasion of MDA‑MB‑231 triple‑negative breast adenocarcinoma cells. Oncol Rep. 2021,46(1):pii: 133. doi: 10.3892/or.2021.8084.
    Read this paper
  • Lu CC, Chiang JH, Tsai FJ, et al. Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. Int J Oncol. 2019,54(4):1271-1281. doi: 10.3892/ijo.2019.4704
    Read this paper
  • Chen CF, Lu CC, Chiang JH, et al. Synergistic inhibitory effects of cetuximab and curcumin on human cisplatin-resistant oral cancer CAR cells through intrinsic apoptotic process. Oncol Lett. 2018,16(5):6323-6330. doi: 10.3892/ol.2018.9418
    Read this paper
  • Cho EC, Kuo ML, Cheng JH, et al. RRM2B-Mediated Regulation of Mitochondrial Activity and Inflammation under Oxidative Stress. Mediators Inflamm. 2015,2015:287345. doi: 10.1155/2015/287345
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  • Sinanoglu O, Yener AN, Ekici S, et al. The protective effects of spirulina in cyclophosphamide induced nephrotoxicity and urotoxicity in rats. Urology. 2012,80(6):1392.e1-6. doi: 10.1016/j.urology.2012.06.053
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  • Tseng HL, Li CJ, Huang LH, et al. Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway. Toxicol Appl Pharmacol. 2012,264(1):104-13. doi: 10.1016/j.taap.2012.07.022
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