p62Dok antibody [N1C1]
GTX101610
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetDOK1
Overview
- SupplierGeneTex
- Product Namep62Dok antibody [N1C1]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1796
- Target nameDOK1
- Target descriptiondocking protein 1
- Target synonymsdocking protein 1; Downstream of tyrosine kinase 1; P62DOK; pp62
- HostRabbit
- IsotypeIgG
- Protein IDQ99704
- Protein NameDocking protein 1
- Scientific DescriptionDocking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach. Sarin N et al., 2018 Mar 7, Int J Mol SciRead more