
WB (peptide competition) analysis of A431 cells stimulated with 100 ng/mL PMA (a phorbol ester activator of protein kinase C) for 30 minutes at 37oC (Lane 2-5) using GTX10697 p90 RSK1 (phospho Ser380) antibody prior incubated with the non-phosphopeptide corresponding to the immunogen (Lane 3), a generic phosphoserine-containing peptide (Lane 4), or, the phosphopeptide immunogen (Lane 5) control. The data show that only the immunogen phosphopeptide blocks the signal, demonstrating the specificity of the antibody.
p90 RSK1 (phospho Ser380) antibody
GTX10697
ApplicationsWestern Blot
Product group Antibodies
ReactivityChicken, Human, Mouse
TargetRPS6KA1
Overview
- SupplierGeneTex
- Product Namep90 RSK1 (phospho Ser380) antibody - Orthogonal Validated
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6195
- Target nameRPS6KA1
- Target descriptionribosomal protein S6 kinase A1
- Target synonyms90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK1; MAPKAPK1A; MAPKAPK-1a; p90Rsk; p90-RSK 1; p90RSK1; p90S6K; ribosomal protein S6 kinase alpha-1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal S6 kinase 1; RSK; RSK1; RSK-1; S6K-alpha 1
- HostRabbit
- IsotypeIgG
- Protein IDQ15418
- Protein NameRibosomal protein S6 kinase alpha-1
- Scientific DescriptionThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- ReactivityChicken, Human, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203