Western Blot Positive WB detected in: 293 whole cell lysate, MCF-7 whole cell lysate, Raji whole cell lysate, HepG2 whole cell lysate All lanes: PABPN1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 33, 32, 38 kDa Observed band size: 50 kDa
Western Blot Positive WB detected in: 293 whole cell lysate, MCF-7 whole cell lysate, Raji whole cell lysate, HepG2 whole cell lysate All lanes: PABPN1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 33, 32, 38 kDa Observed band size: 50 kDa
PABPN1 Recombinant Monoclonal Antibody
CSB-RA569290A0HU
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetPABPN1
Overview
- SupplierCusabio
- Product NamePABPN1 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID6C3
- ConjugateUnconjugated
- Gene ID8106
- Target namePABPN1
- Target descriptionpoly(A) binding protein nuclear 1
- Target synonymsOPMD; PAB2; PABII; PABP2; PABP-2; poly(A) binding protein 2; poly(A) binding protein II; polyadenylate-binding protein 2
- IsotypeIgG
- Protein IDQ86U42
- Protein NamePolyadenylate-binding protein 2
- Scientific DescriptionInvolved in the 3-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (By similarity). Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA. Cooperates with SKIP to synergistically activate E-box-mediated transcription through MYOD1 and may regulate the expression of muscle-specific genes (PubMed:11371506). Binds to poly(A) and to poly(G) with high affinity (By similarity). May protect the poly(A) tail from degradation (By similarity).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
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