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PACMA 31

HY-100433
MedChem Express
CAS Number1401089-31-3
Product group Chemicals
Estimated Purity99.32
Molecular Weight430.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PACMA 31 [1401089-31-3]
  • Delivery Days Customer
    10
  • CAS Number
    1401089-31-3
  • Estimated Purity
    99.32
  • Molecular Formula
    C21H22N2O6S
  • Molecular Weight
    430.47
  • Scientific Description
    PACMA 31 is an irreversible, orally active protein disulfide isomerase (PDI) inhibitor with an IC 50 of 10 microM. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues [1] . PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    COC1=CC=C(N(C(C2=CC=CS2)C(NCC(OCC)=O)=O)C(C#C)=O)C(OC)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200