Pacritinib citrate [1228923-42-9]

TargetMol Chemicals

Pacritinib citrate [1228923-42-9]

16

Research Use Only

C34H40N4O10

664.7

Pacritinib (SB1518) citrate effectively inhibits wild-type JAK2 (IC 50 =23 nM) and the JAK2 V617F mutant (IC 50 =19 nM). It also targets FLT3 (IC 50 =22 nM) and the FLT3 D835Y mutant (IC 50 =6 nM). This compound is utilized in the study of acute myeloid leukemia (AML) and myelofibrosis (MF) [1] [2] [3].

-20°C

12352200