PACS1 antibody

GeneTex

PACS1 antibody

9

WB: 1 - 2 microg/mL. IHC-P: 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

PACS1

phosphofurin acidic cluster sorting protein 1

MRD17, SHMS, phosphofurin acidic cluster sorting protein 1, PACS-1, cytosolic sorting protein PACS-1

Rabbit

IgG

Phosphofurin acidic cluster sorting protein 1

This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the proteases phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203