Pactimibe sulfate [608510-47-0]

TargetMol Chemicals

Pactimibe sulfate [608510-47-0]

86

608510-47-0

Chemical

Research Use Only

Pactimibe sulfate

C50H82N4O10S

931.28

Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor, acting on ACAT1 (IC50: 4.9 microM) and ACAT2 (IC50: 3.0 microM). It inhibits oleoyl-CoA non-competitively (Ki: 5.6 microM) and significantly inhibits cholesterol ester formation (IC50: 6.7 microM). Pactimibe sulfate reduces plasma cholesterol activity and has anti-atherogenic potential.

3 years

OS(O)(=O)=O.CCCCCCCCN1CCc2c1c(NC(=O)C(C)(C)C)c(C)c(CC(O)=O)c2C.CCCCCCCCN1CCc2c1c(NC(=O)C(C)(C)C)c(C)c(CC(O)=O)c2C

-20°C

12352200