
Human tissue extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PAD4 antibody (GTX113945) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
PAD4 antibody
GTX113945
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPADI4
Overview
- SupplierGeneTex
- Product NamePAD4 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration2.85 mg/ml
- ConjugateUnconjugated
- Gene ID23569
- Target namePADI4
- Target descriptionpeptidyl arginine deiminase 4
- Target synonymsPAD, PAD4, PADI5, PDI4, PDI5, protein-arginine deiminase type-4, HL-60 PAD, PADI-H protein, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, protein-arginine deiminase type IV
- HostRabbit
- IsotypeIgG
- Protein IDQ9UM07
- Protein NameProtein-arginine deiminase type-4
- Scientific DescriptionThis gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Kong X, Zhang Y, Xiang L, et al. Fusobacterium nucleatum-triggered neutrophil extracellular traps facilitate colorectal carcinoma progression. J Exp Clin Cancer Res. 2023,42(1):236. doi: 10.1186/s13046-023-02817-8Read this paper
- Indeglia A, Leung JC, Miller SA, et al. An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression. Cancer Discov. 2023,13(7):1696-1719. doi: 10.1158/2159-8290.CD-22-1315Read this paper
- Surolia R, Li FJ, Wang Z, et al. NETosis in the pathogenesis of acute lung injury following cutaneous chemical burns. JCI Insight. 2021,6(10):pii: 147564. doi: 10.1172/jci.insight.147564.Read this paper
- Martins VF, Dobson CR, Begur M, et al. Surgical site peptidylarginine deaminase 4 (PAD4), a biomarker of NETosis, correlates with insulin resistance in total joint arthroplasty patients: A preliminary report. PLoS One. 2021,16(1):e0245594. doi: 10.1371/journal.pone.0245594Read this paper
- Maronek M, Gromova B, Liptak R, et al. Extracellular DNA Correlates with Intestinal Inflammation in Chemically Induced Colitis in Mice. Cells. 2021,10(1). doi: 10.3390/cells10010081Read this paper
- Salemme R, Peralta LN, Meka SH, et al. The Role of NETosis in Systemic Lupus Erythematosus. J Cell Immunol. 2019,1(2):33-42. doi: 10.33696/immunology.1.008Read this paper







![Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PAD4 antibody [N1], N-term (GTX104659) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX104659/GTX104659_39638_20171103_WB_B_w_23060120_406.webp)


