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Human tissue extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PAD4 antibody (GTX113945) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Human tissue extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PAD4 antibody (GTX113945) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Human tissue extract (30 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PAD4 antibody (GTX113945) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

PAD4 antibody

GTX113945
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPADI4
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Overview

  • Supplier
    GeneTex
  • Product Name
    PAD4 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    2.85 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23569
  • Target name
    PADI4
  • Target description
    peptidyl arginine deiminase 4
  • Target synonyms
    PAD, PAD4, PADI5, PDI4, PDI5, protein-arginine deiminase type-4, HL-60 PAD, PADI-H protein, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, protein-arginine deiminase type IV
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UM07
  • Protein Name
    Protein-arginine deiminase type-4
  • Scientific Description
    This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kong X, Zhang Y, Xiang L, et al. Fusobacterium nucleatum-triggered neutrophil extracellular traps facilitate colorectal carcinoma progression. J Exp Clin Cancer Res. 2023,42(1):236. doi: 10.1186/s13046-023-02817-8
    Read this paper
  • Indeglia A, Leung JC, Miller SA, et al. An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression. Cancer Discov. 2023,13(7):1696-1719. doi: 10.1158/2159-8290.CD-22-1315
    Read this paper
  • Surolia R, Li FJ, Wang Z, et al. NETosis in the pathogenesis of acute lung injury following cutaneous chemical burns. JCI Insight. 2021,6(10):pii: 147564. doi: 10.1172/jci.insight.147564.
    Read this paper
  • Martins VF, Dobson CR, Begur M, et al. Surgical site peptidylarginine deaminase 4 (PAD4), a biomarker of NETosis, correlates with insulin resistance in total joint arthroplasty patients: A preliminary report. PLoS One. 2021,16(1):e0245594. doi: 10.1371/journal.pone.0245594
    Read this paper
  • Maronek M, Gromova B, Liptak R, et al. Extracellular DNA Correlates with Intestinal Inflammation in Chemically Induced Colitis in Mice. Cells. 2021,10(1). doi: 10.3390/cells10010081
    Read this paper
  • Salemme R, Peralta LN, Meka SH, et al. The Role of NETosis in Systemic Lupus Erythematosus. J Cell Immunol. 2019,1(2):33-42. doi: 10.33696/immunology.1.008
    Read this paper