Padsevonil

MedChem Express

Padsevonil [1294000-61-5]

10

1294000-61-5

Research Use Only

99.65

C14H14ClF5N4O2S

432.80

Padsevonil (UCB0942) is a potent antiepileptic agent that selectively acts on presynaptic and postsynaptic targets. Padsevonil binds to synaptic vesicular protein 2 ( SV2 ) with high affinity. Padsevonil is also a positive allosteric modulator and partial agonist of GABA A R , with high potency against alpha1 and alpha5 receptors. Padsevonil has antiepileptic effects in a variety of rodent models [1] [2] .

O=C1N(C[C@@H](CC(F)(F)Cl)C1)CC(N(N=C(COC)S2)C2=N3)=C3C(F)(F)F

-20°C,2°C to 8°C

12352200