PAK6 antibody
GTX78127
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Equine, Human, Monkey
TargetPAK6
Overview
- SupplierGeneTex
- Product NamePAK6 antibody
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 3.5 microg/ml. IHC-P: 3.5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID56924
- Target namePAK6
- Target descriptionp21 (RAC1) activated kinase 6
- Target synonymsp21 protein (Cdc42/Rac)-activated kinase 6; p21(CDKN1A)-activated kinase 6; PAK5; serine/threonine-protein kinase PAK 6
- HostRabbit
- IsotypeIgG
- Protein IDQ9NQU5
- Protein NameSerine/threonine-protein kinase PAK 6
- Scientific DescriptionThis gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
- ReactivityCanine, Equine, Human, Monkey
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Predictive value of PAK6 and PSMB4 expression in patients with localized prostate cancer treated with dose-escalation radiation therapy and androgen deprivation therapy. Zapatero A et al., 2014 Nov, Urol OncolRead more