Palazestrant [2092925-89-6]

MedChem Express

Palazestrant [2092925-89-6]

10

2092925-89-6

Research Use Only

99.90

C28H36FN3O

449.60

Palazestrant is an antiestrogen and antineoplastic agent. Palazestrant can completely inhibit the activity of 17b-estradiol (E2) with IC50 value of 6.4 nM, and inhibit the proliferation of MCF7 and CAMA-1 cells with IC50 value of 1.4-1.6 nM. Palazestrant can inhibit ER+/HER2+ cancer[1][2][3].

CC(C)(F)CN1[C@H](C2=CC=C(C=C2)OC3CN(C3)CCC)C4=C(C[C@H]1C)C5=CC=CC=C5N4

-20°C,2°C to 8°C

12131703