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Palbociclib (hydrochloride)

HY-50767C
MedChem Express
CAS Number571189-11-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.93
Molecular Weight514.99
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Palbociclib (hydrochloride) [571189-11-2]
  • Delivery Days Customer
    10
  • CAS Number
    571189-11-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.93
  • Molecular Formula
    C24H29N7O2.37/20ClH
  • Molecular Weight
    514.99
  • Scientific Description
    Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4] .
  • SMILES
    O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(N5CCNCC5)C=N4)C.Cl.[37/20]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200