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Palbociclib (isethionate)

HY-A0065
MedChem Express
CAS Number827022-33-3
Product group Chemicals
Estimated Purity99.99
Molecular Weight573.66
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Palbociclib (isethionate) [827022-33-3]
  • Delivery Days Customer
    10
  • CAS Number
    827022-33-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.99
  • Molecular Formula
    C26H35N7O6S
  • Molecular Weight
    573.66
  • Scientific Description
    Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4] .
  • SMILES
    CC(C1=C(N2C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C1)=C(C(C)=O)C2=O.OCCS(O)(=O)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200