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Palbociclib (monohydrochloride)

HY-50767A
MedChem Express
CAS Number827022-32-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.98
Molecular Weight483.99
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Palbociclib (monohydrochloride) [827022-32-2]
  • Delivery Days Customer
    10
  • CAS Number
    827022-32-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.98
  • Molecular Formula
    C24H30ClN7O2
  • Molecular Weight
    483.99
  • Scientific Description
    Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4] .
  • SMILES
    O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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