Palifosfamide (tromethamine) [1070409-31-2]
HY-114577
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NamePalifosfamide (tromethamine) [1070409-31-2]
- Delivery Days Customer10
- CAS Number1070409-31-2
- CertificationResearch Use Only
- Molecular FormulaC8H22Cl2N3O5P
- Molecular Weight342.16
- Scientific DescriptionPalifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.
- SMILESO=P(NCCCl)(NCCCl)O.NC(CO)(CO)CO
- UNSPSC41115800