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Palmatine (chloride)

HY-N0110
MedChem Express
CAS Number10605-02-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.81
Molecular Weight387.86
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Palmatine (chloride) [10605-02-4]
  • Delivery Days Customer
    10
  • CAS Number
    10605-02-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.81
  • Molecular Formula
    C21H22ClNO4
  • Molecular Weight
    387.86
  • Scientific Description
    Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC 50 s of 3 microM and 157microM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC 50 of 96 microM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities [1] [2] [3] [4] [5] .
  • SMILES
    COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(OC)C=C4CC3)C=C2C=C1.[Cl-]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200