PAM, Human (HEK293, Fc)
HY-P73732
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NamePAM, Human (HEK293, Fc)
- Delivery Days Customer10
- CertificationResearch Use Only
- Gene ID5066
- Target namePAM
- Target descriptionpeptidylglycine alpha-amidating monooxygenase
- Target synonymsPAL, PAM-1, PHM, peptidyl-glycine alpha-amidating monooxygenase, pancreatic peptidylglycine alpha-amidating monooxygenase, peptidyl alpha-amidating enzyme, peptidyl-alpha-hydroxyglycine alpha-amidating lyase, peptidylamidoglycolate lyase, peptidylglycine 2-hydroxylase, peptidylglycine alpha-hydroxylating monooxygenase
- Scientific DescriptionThe PAM protein is a bifunctional enzyme that coordinates the alpha-amidation process, which is critical for the biosynthesis of neuropeptides and endocrine peptides. The peptidyl alpha-hydroxylating monooxygenase (PHM) domain hydroxylates the C-terminal glycine, and the peptidylglycine amide glycolate lyase (PAL) domain cleaves the NC-alpha bond, producing alpha-amidated peptides. PAM Protein, Human (HEK293, Fc) is the recombinant human-derived PAM protein, expressed by HEK293 , with C-hFc labeled tag.
- UNSPSC41116100
- SpeciesHuman