Pam3Cys-Ser-(Lys)4 . trihydrochloride [112208-00-1]

AdipoGen Life Sciences

Pam3Cys-Ser-(Lys)4 . trihydrochloride

10

112208-00-1

Research Use Only

1 mg/ml

Warning

C81H156N10O13S . 3HCl

1510.3 . 109.4

Chemical. CAS: 112208-04-5. Formula: C81H156N10O13S . 3HCl. MW: 1510.3 . 109.4. Synthetic. Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response, enhances IgG2a and IgG1 titers and upregulates proinflammatory and Th1 cytokine genes. Potent activator of the proinflammatory transcription factor NF-kappaB. - Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response, enhances IgG2a and IgG1 titers and upregulates proinflammatory and Th1 cytokine genes. Potent activator of the proinflammatory transcription factor NF-kappaB.

CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](CO)C(=O)C(=O)[C@H](CCCCN)NN[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O

-20°C,2°C to 8°C

12352200