pan-KRAS-IN-5 [3027172-23-9]

TargetMol Chemicals

pan-KRAS-IN-5 [3027172-23-9]

16

Research Use Only

C31H36FIN4O2

642.55

Pan-KRAS-IN-5 (compound 15a) is a pan-KRAS translation inhibitor targeting 5-UTR RNA G-quadruplexes (rG4s). It induces cell cycle arrest and promotes apoptosis in KRAS-driven cancer cells [1].

C[N+]=1C2=C(C=C(F)C(NCCN3CCCC3)=C2)C=CC1/C=C/C4=CC=5C(OC4=O)=CC(N(CC)CC)=CC5.[I-]

-20°C

51202000