Pantothenate-AMC [1224691-12-6]

MedChem Express

Pantothenate-AMC [1224691-12-6]

5

Research Use Only

C19H24N2O6

376.40

Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively[1].

CC(C1=CC=C(NC(CCNC([C@H](O)C(C)(C)CO)=O)=O)C=C1O2)=CC2=O

12352200