PAOPA

MedChem Express

PAOPA [114200-31-6]

10

114200-31-6

Research Use Only

97.68

C11H18N4O3

254.29

PAOPA, an analog of L-proline-l-leucine-glycine amide (PLG) peptide, is an allosteric modulator of Dopamine D2 Receptor. PAOPA can effectively reduce behavioral abnormalities in rodent models of schizophrenia. PAOPA increases the high affinity dopamine D2 receptor and promotes its binding to agonists[1].

O=C([C@@H]1CCCN1)N[C@H]2C(N(CC2)CC(N)=O)=O

-20°C

12352200