WB analysis of HeLa cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX85150 PLAC3 antibody. Working concentration : 1 microg/ml
WB analysis of HeLa cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX85150 PLAC3 antibody. Working concentration : 1 microg/ml
Pappalysin 2 antibody
GTX85150
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPAPPA2
Overview
- SupplierGeneTex
- Product NamePappalysin 2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 microg/mL. ICC/IF: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID60676
- Target namePAPPA2
- Target descriptionpappalysin 2
- Target synonymsPAPP-A2; pappalysin-2; PAPPE; PAPP-E; PLAC3; placenta-specific 3; pregnancy-associated plasma preproprotein-A2; pregnancy-associated plasma protein E1; SSDA
- HostRabbit
- IsotypeIgG
- Protein IDQ9BXP8
- Protein NamePappalysin-2
- Scientific DescriptionPLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203