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Parathyroid Hormone (PTH) (N-Terminal), CF405S conjugate, 0.1mg/mL [26628-22-8]

Parathyroid Hormone (PTH) (N-Terminal), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC041728
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Deer, Human, Porcine, Primate, Rabbit, Rat
TargetPTH
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Overview

  • Supplier
    Biotium
  • Product Name
    Parathyroid Hormone (PTH) (N-Terminal), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID5741
  • Target name
    PTH
  • Target description
    parathyroid hormone
  • Target synonyms
    FIH1; parathormone; parathyrin; parathyroid hormone; parathyroid hormone 1; preproparathyroid hormone; prepro-PTH; PTH1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01270
  • Protein Name
    Parathyroid hormone
  • Scientific Description
    Epitope of this PAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Canine, Deer, Human, Porcine, Primate, Rabbit, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203