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Park7 / DJ-1 antibody

GTX132552
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetPARK7
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Overview

  • Supplier
    GeneTex
  • Product Name
    Park7 / DJ-1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID11315
  • Target name
    PARK7
  • Target description
    Parkinsonism associated deglycase
  • Target synonyms
    DJ1; DJ-1; epididymis secretory sperm binding protein Li 67p; GATD2; HEL-S-67p; maillard deglycase; oncogene DJ1; Parkinson disease (autosomal recessive, early onset) 7; Parkinson disease protein 7; parkinson protein 7; protein deglycase DJ-1; protein DJ-1; protein/nucleic acid deglycase DJ-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ99497
  • Protein Name
    Protein/nucleic acid deglycase DJ-1
  • Scientific Description
    The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Brain region-specific susceptibility of Lewy body pathology in synucleinopathies is governed by alpha-synuclein conformations. de Boni L et al., 2022 Apr, Acta Neuropathol
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  • Methylglyoxal and D-lactate in cisplatin-induced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis. Chen SM et al., 2020, PLoS One
    Read more