WB analysis of various sample lysates using GTX65812 Parkin antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX65812 Parkin antibody. Dilution : 1:1000 Loading : 25microg per lane
Parkin antibody
GTX65812
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetPRKN
Overview
- SupplierGeneTex
- Product NameParkin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5071
- Target namePRKN
- Target descriptionparkin RBR E3 ubiquitin protein ligase
- Target synonymsAR-JP; E3 ubiquitin-protein ligase parkin; LPRS2; PARK2; Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); PDJ
- HostRabbit
- IsotypeIgG
- Protein IDO60260
- Protein NameE3 ubiquitin-protein ligase parkin
- Scientific DescriptionThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203