PARP-1-IN-2 [684234-55-7]

MedChem Express

PARP-1-IN-2 [684234-55-7]

10

684234-55-7

Research Use Only

99.48

C22H15Cl2N3O2

424.28

PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 149 nM. PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. PARP1-IN-2 can induce A549 cells apoptosis[1].

O=C(NC1=CC=CC(Cl)=C1)CN(N=C(C2=CC=C(Cl)C=C2)C3=C4C=CC=C3)C4=O

2°C to 8°C

12131703