PARP-2 [ARTD2] (mouse) (rec.) (His) (high purity)

AdipoGen Life Sciences

PARP-2 [ARTD2] (mouse) (rec.) (His) (high purity)

10

Research Use Only

>98%

Poly [ADP-ribose] polymerase 2

PARP-2 [ARTD2] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. - Protein. Mouse full-length PARP-2 [ARTD2] is fused to a His-tag. Source: Sf21 cells. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. Purity: >98% (SDS-PAGE). PARP-2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

-20°C,-80°C

12352202