PARP1-IN-8 [836640-15-4]

MedChem Express

PARP1-IN-8 [836640-15-4]

10

836640-15-4

Research Use Only

99.29

C23H18ClN3O2

403.86

PARP1-IN-8 (compound 11c) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 97 nM. PARP1-IN-8 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549[1].

O=C(NC1=CC=CC(Cl)=C1)CCN(N=C(C2=CC=CC=C2)C3=C4C=CC=C3)C4=O

2°C to 8°C

12131703