PARP14 inhibitor H10

MedChem Express

PARP14 inhibitor H10 [2084811-68-5]

5

2084811-68-5

Research Use Only

98.04

C24H27N7O7S

557.58

PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (~24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1].

O=C(O)C1=CC=CC(S(=O)(NCCN2N=NC(CCNC(CCC(NC3=CC=CC(C(N)=O)=C3)=O)=O)=C2)=O)=C1

-20°C,2°C to 8°C

12352200