Parsaclisib

Biorbyt

Parsaclisib [1426698-88-5]

10

1426698-88-5

Research Use Only

C20H22CLFN6O2

432.879086

Parsaclisib (INCB050465) is a potent, selective and orally active inhibitor of PI3Kdelta, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib can be used for the research of relapsed or refractory B-cell malignancies.

ClC1C=C(C(=C(C=1F)[C@H]1CC(NC1)=O)OCC)[C@H](C)N1C2C(=C(N)N=CN=2)C(C)=N1

12352200