Pazopanib

MedChem Express

Pazopanib [444731-52-6]

10

444731-52-6

Research Use Only

99.91

C21H23N7O2S

437.529

Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1 , VEGFR2 , VEGFR3 , PDGFRbeta , c-Kit , FGFR1 , and c-Fms with IC 50 s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.

O=S(C1=CC(NC2=NC=CC(N(C3=CC4=NN(C(C)=C4C=C3)C)C)=N2)=CC=C1C)(N)=O

-20°C,2°C to 8°C

12352200