PB28
HY-108511A
Overview
- SupplierMedChem Express
- Product NamePB28 [172906-90-0]
- Delivery Days Customer10
- CAS Number172906-90-0
- CertificationResearch Use Only
- Molecular FormulaC24H38N2O
- Molecular Weight370.57
- Scientific DescriptionPB28 is a cyclohexylpiperazine derivative and a high affinity and selective sigma 2 (sigma2) receptor agonist with a Ki of 0.68 nM. PB28 is also a sigma1 antagonist with a Ki of 0.38 nM. PB28 is less affinity for other receptors. PB28 inhibits electrically evoked twitch in guinea pig bladder and ileum with EC50 values of 2.62 microM and 3.96 microM, respectively. PB28 can modulate SARS-CoV-2-human protein-protein interaction. PB28 induces caspase-independent apoptosis and has antitumor activity[1][2][3][4][5].
- SMILESCOC1=CC=CC2=C1CCCC2CCCN3CCN(C4CCCCC4)CC3
- UNSPSC12352200
Related products
![PB28 [172906-90-0]](https://www.targetmol.com/group3/M00/02/DE/CgoaEGY7QEWEaf5JAAAAAH5p6cQ075.png)
Product group Chemicals
PB28 [172906-90-0]T39176
CAS Number172906-90-0
Molecular Weight370.581
- SizePrice
Product group Chemicals
PB28ORB1691511
CAS Number172906-90-0
Estimated Purity98%
Molecular Weight370.581
- SizePrice
