PBD dimer-4
HY-175004
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NamePBD dimer-4
- Delivery Days Customer999
- CertificationResearch Use Only
- Molecular FormulaC31H36N4O8
- Molecular Weight592.64
- Scientific DescriptionPBD dimer-4 (Compound 7) is a C1-subsitituted PBD dimer. PBD dimer-4 has high DNA-binding affinity, DNA cross-linking ability and potent cytotoxicity against MDA-MB-231 cells (IC50: 236 nM). PBD dimer-4 can be used as a payload of ADC Loncastuximab tesirine (HY-P99349) to treat several different cancer types[1].
- SMILES[H][C@]12C=NC3=CC(OC)=C(C=C3C(N1CC[C@@H]2OCCCO[C@H]4CCN5C(C6=CC(OC)=C(C=C6N=C[C@]45[H])OC)=O)=O)OC
- UNSPSC41115800