PBIT

MedChem Express

PBIT [2514-30-9]

10

2514-30-9

Research Use Only

99.46

C14H11NOS

241.31

PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 ( JARID1 ) enzymes. PBIT inhibits JARID1B ( KDM5B or PLU1 ) histone demethylase with an IC 50 of about 3 microM . PBIT also inhibits JARID1A and JARID1C with IC 50 s of 6 microM and 4.9 microM, respectively [1] .

O=C1N(C2=CC=C(C)C=C2)SC3=C1C=CC=C3

-20°C

12352200