Bio-Connect

PBIT

M15089
AbMole BioScience
CAS Number2514-30-9
Product group Chemicals
Molecular Weight241.31
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    PBIT
  • Delivery Days Customer
    9
  • CAS Number
    2514-30-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C14H11NOS
  • Molecular Weight
    241.31
  • Scientific Description
    PBIT is a JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor with IC50 values of 3, 4.9 and 6 uM for JARID1B, 1A and 1C, respectively. It can increase trimethylation of H3K4 in HeLa cells and block the proliferation of tumor cells expressing high levels of JARID1B.
  • SMILES
    CC1=CC=C(C=C1)N2SC3=CC=CC=C3C2=O
  • Storage Instruction
    2-8°C
  • UNSPSC
    12352200