Bio-Connect

PBT434 [1232841-78-9]

HY-120475
MedChem Express
CAS Number1232841-78-9
Product group Chemicals
Estimated Purity98.86
Molecular Weight383.07
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    PBT434 [1232841-78-9]
  • Delivery Days Customer
    5
  • CAS Number
    1232841-78-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.86
  • Molecular Formula
    C12H14BrCl2N3O2
  • Molecular Weight
    383.07
  • Scientific Description
    PBT434 is a potent, orally active and cross the blood-brain barrier alpha-synuclein aggregation inhibitor. PBT434 can be used as a iron chelator and modulates transcellular iron trafficking. PBT434 inhibits iron-mediated redox activity and iron-mediated aggregation of alpha-synuclein. PBT434 prevents the loss of substantia nigra pars compacta neurons (SNpc). PBT434 has the potential for the research of Parkinsons disease (PD)[1].
  • SMILES
    O=C1N(C)C(CNCC)=NC2=C1C(Cl)=CC(Cl)=C2O.Br
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200