Bio-Connect

PC945 [1931946-73-4]

HY-117766
MedChem Express
CAS Number1931946-73-4
Product group Chemicals
Estimated Purity99.27
Molecular Weight682.73
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PC945 [1931946-73-4]
  • Delivery Days Customer
    9
  • CAS Number
    1931946-73-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.27
  • Molecular Formula
    C38H37F3N6O3
  • Molecular Weight
    682.73
  • Scientific Description
    PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14alpha-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 microM and 0.22 microM, respectively[1][2].
  • SMILES
    O=C(NC1=CC=C(F)C=C1)C(C=C2)=CC=C2N3CCN(C4=CC=C(OC[C@@H]5CO[C@](C6=CC=C(F)C=C6F)(CN7N=CN=C7)C5)C(C)=C4)CC3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200