Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA705514LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA705514LA01HU at dilution of 1:100
PCID2 Antibody
CSB-PA705514LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPCID2
Overview
- SupplierCusabio
- Product NamePCID2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID55795
- Target namePCID2
- Target descriptionPCI domain containing 2
- Target synonymsCSN12-like protein; F10; PCI domain-containing protein 2
- HostRabbit
- IsotypeIgG
- Protein IDQ5JVF3
- Protein NamePCI domain-containing protein 2
- Scientific DescriptionRequired for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203